MICR 142 Cellular and Molecular Mechanisms in Immune Defense

This course consists of a series of lectures that cover the field of Immunology including both normal and disease related aspects. Focus will be on the basic cellular and molecular components involved in antigen specific and non-specific immune responses. We will cover the mechanisms associated with cellular and humoral immunity, the development of allergies, autoimmunity, immunodeficiency diseases, graft rejection, the role of the immune system in preventing and treating cancer, and the immune response to pathogens. The course is divided into four parts, each ending with a written, in-class examination. Graded assignments will be given weekly. During the second half of the class, graduate students will be required to present assigned literature dealing with research in a disease-related aspects of immunology.

Exams and Assignments: Grades are based on three in-class examinations, eight homework assignments, a final exam, and one literature presentation. Exams consist of 100 points each, broken up into multiple choice (50 points) and short answer (50 points) sections. Eight homework assignments (12.5 points each), will be administered throughout the term for a total of 100 points. The Final Exam is worth 200 points, with one half on material from the last part of the course, and the other half being cumulative.

Literature Presentations: Each Micro142 student will be required to give an in-class presentation on literature related to an immunological topic in Autoimmunity and Hypersensitivity, Infections and Vaccines, or Tumor Immunology or Transplantation Tolerance. Presentation topics, associated literature, and dates will be assigned at the beginning of the term. A grade will be assigned for the presentation out of 100 points. 

Instructor

Turk and associates

Prerequisite

A prior immunology course: BIOC 102, BIOL 046, or permission of the instructor